Sampling the visual field based on individual retinal nerve fiber layer thickness profile

Abstract

PURPOSE. Current perimeters use fixed grid patterns. We test whether a grid based on an individual’s retinal nerve fiber layer (RNFL) thickness profile would find more visual field (VF) defects. METHODS. We describe the defect-based method for choosing test locations. First, the 26 VF locations with the highest positive predictive value to detect glaucoma from the 24-2 pattern are chosen. An additional 26 locations are chosen from a 2 × 2 degree grid based on RNFL thickness. An individualized map was used to relate VF locations to peripapillary RNFL thickness. To test whether the 52 locations chosen by the defect-based method find more defects than other test grids, we collected a 386-locati..